Soursop: The Vitamin C Superfruit that May Help Fight Cancer

Soursop: The Vitamin C Superfruit that May Help Fight Cancer

What if I told you there was a fruit that’s great for your eyes, can treat infections and even shows promise as a potential cancer-fighting food? Would you be interested? If you answered yes — and why wouldn’t you? — let me introduce you to soursop.

Soursop is usually found in South America and often the basis for beverages, ice creams and other popular sweets. It’s known to have a few other names, such as graviola, custard apple, pawpaw, guyabano and guanabana in English and Spanish-speaking countries alike. Additionally, it has superfruit-healing properties as a high-antioxidant food due to its vitamin C, B vitamins, calcium, phosphorous and even some iron that it contains. These vitamins and minerals are why soursop benefits include potentially helping reduce eye disease, treat infections and potentially even fight cancer.

Soursop - Dr. AxeBenefits of Soursop

1. Filled with Beneficial Antioxidants that May Help Reduce Eye Disease

Many of the potential guanabana benefits are thought to be derived from its antioxidant properties. (1) Studies show that the phytonutrients found in the fruit are high in antioxidant compounds, including alkaloids, saponins, terpenoids, flavonoids, coumarins, lactones, anthraquinones, tannins, cardiac glycosides, phenols and phytosterols. This is quite a group that can help fight disease-causing cells and even block tumor growth. (2

Additional studies have reported that antioxidants may also help with eye disease. The Age-Related Eye Disease Study led by the National Eye Institute found antioxidants to be useful, especially when consumed as a cocktail of vitamin C, vitamin E, beta-carotene and zinc. In one study, this combination actually lowered the risk of developing age-related macular degeneration by 25 percent in those who already had the disease. (3)

2. Exhibits Anti-Inflammatory and Antimicrobial Properties

Extracts from graviola leaves have shown anti-inflammatory properties in addition to their antimicrobial characteristics, making soursop a versatile anti-inflammatory food. Studies indicate that soursop may also be a natural anti-infection treatment for root canals. Often dangerous chemicals, such as sodium hypochlorite (a form of bleach), are used to irrigate the root canal to prevent infection. However, the dangers of these chemicals can pose health hazards. A study published in the Journal of Contemporary Dental Practice shows that the use of graviola to irrigate the root canal is very effective, making it a much healthier option. (4)

3. May Help Fight Cancer

If you’ve ever wondered which fruits are good for cancer patients, soursop may top the charts due to its anti-cancer effects. Research published in Food & Function reports that bioactive components of graviola leaf extracts may have positive cancer-fighting properties. This is due to the free radical scavenging abilities and antioxidant enzymes they contain, thus helping to eliminate cancer cells. (5) It’s believed that the guanabana leaves kill cancer cells by blocking ATP production. ATP, aka adenosine triphosphate, is a usable form of energy for cells. This energy is contained within a chemical bond that, if released, can be used to foster other activity within the cells. (6)

However, the graviola leaf extract can help block this activity, which may reduce the impact of the cancer cells by breaking them down until they fall apart. This is known as apoptosis or programmed cell death. Additionally, scientists at the Tepic Institute of Technology (Instituto Tecnológico de Tepic – ITT) in Mexico discovered acetogenins in the soursop fruit, which hold potent chemotherapeutic properties. (7)

So is gaunabana good for cancer? Keep in mind that current research is limited to in vitro studies, so it’s difficult to determine how soursop may affect the growth and development of cancer cells in humans. More studies are needed before experts can really determine whether the anti-cancer effects of soursop apply to the general population as well. It does, however, show potential as a cancer-fighting food.

4. Potentially Kills Pancreatic Cancer Cells

Graviola extract has shown an ability to help kill numerous types of cancer cells, specifically pancreatic cancer cells. A study conducted by the University of Nebraska Medical Center found that the extract can greatly reduce pancreatic cancer. Because cancer cells have more glucose, cell growth is typically enhanced as well as tumor growth. However, in this study, cells that were treated with graviola extract decreased their glucose uptake when compared to untreated cells. This decrease can make it difficult for the bad cells to multiply and grow. This helps block the spread of cancer. (8)

5. Treats Infections

Graviola is often used to treat infections caused by bacteria and parasites, including leishmaniasis. Leishmaniasis is a disease that’s transmitted through the bite of sand fleas. It’s also been used to treat herpes, coughing and vomiting. Bacterial and viral infections can cause coughing, sneezing, fever and more symptoms. While these symptoms may be frustrating, they’re effective since they’re part of the method that the body uses to trigger the immune system to get to work ridding the body of any infection. Graviola and graviola tea may be able to efficiently fight the infection and get you back on your feet. (9


All about soursop - Dr. Axe

Related: Top 7 Benefits of Green Tea: The No. 1 Anti-Aging Beverage

Nutrition Facts

A 100-gram serving of raw soursop contains about: (10)

  • 66 calories
  • 16.8 grams carbohydrates
  • 1 gram protein
  • 0.3 gram fat
  • 3.3 grams fiber
  • 20.6 milligrams vitamin C (34 percent DV)
  • 278 milligrams potassium (8 percent DV)
  • 0.1 milligram thiamine (5 percent DV)
  • 21 milligrams magnesium (5 percent DV)
  • 0.9 milligram niacin (4 percent DV)
  • 0.1 milligram copper (4 percent DV)
  • 0.1 milligram riboflavin (3 percent DV)
  • 0.1 milligram vitamin B6 (3 percent DV)
  • 14 micrograms folate (3 percent DV)
  • 0.6 milligram iron (3 percent DV)
  • 27 milligrams phosphorus (3 percent DV)
  • 0.3 milligram pantothenic acid (3 percent DV)


Soursop is used in many foods. These include guanabana juice, soft drinks, ice creams, cheesecakes, milkshakes, candies and custards. It’s also used in soups and even roasted or fried like vegetables. The leaves are often also dried and brewed into a guanabana tea, which is believed to be beneficial for a wide array of health conditions. It’s recommended that you avoid eating the seeds due to possible neurotoxins. However, the raw flesh of the fruit is a wonderful way to experience to true essence of the soursop.

Traditionally, soursop can be cut into segments and eaten raw. Make sure to choose one that’s very soft. If it’s green, simply allow it to ripen on the countertop or in the fridge, similar to ripening an avocado or mango. To cut it, use a knife and cut through it longways. Inside, you will find a custard-like, cream-colored flesh. To eat it, just use a spoon and scoop it out. It has a sour and sweet taste similar to the combination of a banana-pineapple flavor and emits a tropical fruit-like scent that’s a bit musky.

Wondering where to buy guanabana? This powerful fruit is available in many specialty stores and ethnic markets. It can also be purchased online and is widely available in liquid extract, tea and supplement form.

If you’re looking for soursop recipes, try this one to start:

Soursop and Cinnamon Milkshake


  • 1 ripe soursop
  • 1/2 cup coconut water
  • ½ cup almond milk
  • 1 medium frozen banana
  • 1/8 teaspoon nutmeg
  • ⅛ teaspoon cinnamon
  • 1 teaspoon vanilla flavoring


  1. In a blender, place the soursop, coconut water and almond milk. Blend until smooth.
  2. Then add the remaining ingredients and blend until smooth.
  3. For a thicker shake, use less liquid ingredients. For a thinner shake, add more almond milk.
  4. Once you have the shake at your desired consistency, pour into a glass and sprinkle the top with cinnamon.
  5. Add a cinnamon stick for a nice touch.

Here are a couple more soursop recipes to try:


Often associated with other tropical fruits due to its distinct appearance, many people wonder: Are jackfruit and guanabana the same thing? Though not quite as large as the jackfruit, soursop fruit still holds some weight. It comes in at anywhere from four to 12 inches wide, up to six inches long and may weigh up to 15 pounds. It grows from a guanabana tree that can reach up to 30 feet in height. This tropical fruit is usually oval or heart-shaped. It can be irregular in shape, mainly due to issues with insects during development. Soursop has a spiny skin that’s not edible. The skin is dark green until mature, when it becomes yellowish green in color. It has a similar scent and flavor to the pineapple but a bit musky in flavor as well. The flesh is an off-white color, granular, fibrous and juicy. It grows in segments where there is an oval, smooth, hard, black seed, about 1/2 to 3/4 inch long. It contains anywhere from a few dozen to 200 or more seeds.

One of the very first fruit trees literally carried from America to Southeastern China, Australia and Western Africa, soursop has been noted by Oviedo as an abundant fruit as early as 1526. It has grown in Florida for nearly 110 years and was listed by the American Pomological Society in 1879 as a Florida fruit. It’s often found in home gardens. Cuban soursop began selling to Key West, Fla., in 1887 from 10 cents to 50 cents each. Colombia produces the highest-quality soursop and is one of the 14 tropical fruits that the Instituto Latinoamericano de Mercadeo Agricola has noted as strong for large-scale planting and marketing.

Soursops are produced in small plots throughout Venezuela, which provides the supply for the processing plants where the frozen concentrate is manufactured, and the strained pulp is preserved commercially in Costa Rica.


Risks and Side Effects

While some experts claim that soursop can have negative effects on the body, further studies are needed. Don’t take graviola supplements if pregnant or breastfeeding or on medications. The effects have not been studied, and they may come with adverse side effects.

The seeds of soursop should be avoided. They contain high amounts of annonacin, a neurotoxin that has been linked to Parkinson’s disease and other neurological disorders. (11) Similarly, another study reported that consuming a tea made from the leaves and stems of the fruit could be associated with neurotoxicity as well. (12)

Furthermore, keep in mind that current research on the cancer-fighting benefits of soursop is currently limited to in vitro studies. Although many retailers and supplement shops may advertise natural guanabana cancer treatments, more studies are needed to understand how soursop may impact cancer development in humans. Consult with your doctor before taking soursop supplements, and decrease your dosage if you have any concerns or experience adverse side effects.

Final Thoughts

The soursop fruit may be hugely beneficial for anyone fighting cancer, but it’s important to note that more studies need to be conducted. Use it with caution and do as much research as possible to help identify if this superfruit can help you or anyone you know who may be fighting cancer or other disease.

The good news is it’s been shown to have potential cancer-fighting effects, along with treating infection, possessing anti-inflammatory and antimicrobial abilities, and benefiting eye health. If you have no adverse effects, this fruit may be for you.

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